Unsubstituted Phenols
Medchemexpress LLC HY-12000 10mg Medchemexpress, AG-490 CAS:133550-30-8 Purity:>98%
Medchemexpress, HY-12000 10mg AG-490 CAS:133550-30-8 AG-490 is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules Medchem Express / Erianin / 5mg / 437899664 / HY-N0517 / / 95041-90-0 / MFCD06795132 / 318.369 / C18H22O5
Medchem Express / Erianin / 5mg / 437899664 / HY-N0517 / / 95041-90-0 / MFCD06795132 / 318.369 / C18H22O5
Medchemexpress LLC HY-B0167A 10g Medchemexpress, Sodium Salicylate CAS:54-21-7 Purity:>98%
Medchemexpress, HY-B0167A 10g Sodium Salicylate CAS:54-21-7 Sodium Salicylate inhibits cyclo-oxygenase-2 ( COX-2 ) activity independently of transcription factor (NF-κB) activation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC IKK-16 hydrochloride | 1186195-62-9 | MFCD09971091 | 100.0% | 520.09 g·mol⁻¹ | C28H30ClN5OS | 5 MG
IKK-16 hydrochloride is the hydrochloride salt form of a selective IκB kinase (IKK) inhibitor used in research to modulate NF-κB signaling pathways. It is provided as a characterized research reagent for biochemical and cellular studies where inhibition of IKK is required.
- Selective inhibition of IκB kinase to modulate NF-κB signaling.
- Suitable for biochemical and cellular assays.
- High reported purity for reliable experimental results.
- Hydrochloride salt form improves solubility in common solvents.
- Available in small quantities for research workflows.
Medchemexpress LLC Licochalcone B | 58749-23-8 | 286.28 | 1 MG
Licochalcone B is an extract from the root of *Glycyrrhiza uralensis*. It inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregates pre-formed Aβ42 fibrils. It also reduces metal-induced Aβ42 aggregation by chelating metal ions. Licochalcone B inhibits the phosphorylation of NF-κB p65 in the LPS signaling pathway, inhibits the growth and induces apoptosis of NSCLC cells, and specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction.
- Inhibits amyloid β (42) self-aggregation and disaggregates pre-formed Aβ42 fibrils.
- Reduces metal-induced Aβ42 aggregation through chelating metal ions.
- Inhibits phosphorylation of NF-κB p65 in the LPS signaling pathway.
- Inhibits growth and induces apoptosis of NSCLC cells.
- Specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction.
- Purity: 99.91%.
Selleck Chemical LLC 2 4-Dihydroxybenzoic acid
2 4-Dihydroxybenzoic acid ( -resorcylic acid p-Hydroxysalicylic acid) is a degradation product of cyanidin glycosides from tart cherries in cell cultures and a metabolite found in human plasma after cranberry juice consumption
Apexbio Technology LLC Honokiol 35354-74-6 20mg
Honokiol (CAS 35354-74-6) is a small-molecule inhibitor targeting nuclear factor-kappa B (NF- B) It is designed to modulate NF- B activation induced by stimuli such as TNF and okadaic acid thereby regulating inflammatory and oncogenic signaling pathways Honokiol exerts its biological activity primarily through inhibition of NF- B activation and free radical scavenging In cell-based studies honokiol demonstrates antiproliferative and antiangiogenic activity with IC50 values ranging from approximately 10 M to 50 M depending on cell types and experimental conditions Based on these pharmacological properties honokiol holds research potential in studying inflammation signaling oxidative stress mechanisms tumor biology and angiogenesis inhibition
Apexbio Technology LLC Phenol Red sodium salt 34487-61-1 5g
Phenol Red sodium salt (34487-61-1) is a small molecule compound binding to estrogen receptors It can interact with estrogen receptors thereby modulating downstream signaling pathways and associated cellular processes Phenol Red sodium salt functions primarily via estrogen receptor affinity In cell-based studies it binds to estrogen receptors in human breast cancer cell lines such as MCF-7 cells Based on these properties Phenol Red sodium salt holds research potential in oncology studies particularly those investigating hormone-mediated signaling pathways and receptor-mediated cellular responses
eMolecules Medchem Express / BHPI / 5mg / 446261892 / HY-12825 / / 56632-39-4 / MFCD01919164 / 331.371 / C21H17NO3
Medchem Express / BHPI / 5mg / 446261892 / HY-12825 / / 56632-39-4 / MFCD01919164 / 331.371 / C21H17NO3
Apexbio Technology LLC Deoxyarbutin 53936-56-4 50mg
Deoxyarbutin (CAS 53936-56-4) is a small molecule that acts as a reversible inhibitor of tyrosinase a key enzyme involved in melanin biosynthesis By targeting tyrosinase Deoxyarbutin effectively suppresses enzymatic activity exhibiting an IC50 value of 50 nM in inhibition assays This compound is widely utilized in biomedical research to study melanogenesis explore regulatory mechanisms of skin pigmentation and evaluate potential therapeutic approaches for pigmentary disorders